- Human(11)
- Mouse(5)
- Mus musculus (Mouse)(1)
- Rat(1)
Active Recombinant Mouse Interleukin 27 Receptor, Alpha, Fc-tagged
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Cat.No. : | Il27ra-660M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Mouse Il27raprotein was expressed in Murine myeloma cell line with the Fc part of humanIgG1 Pro100-Lys330 (C-terminus) and Gly29-Lys510 (N-terminus). |
Description : | Il27ra (also knownas WSX1 and TCCR) is an 85-95 kDa member of the type I, group 2 cytokinereceptor family. Mature Il27ra is a type I transmembrane glycoprotein thatcontains a 486 amino acids extracellular region, a 21 aa transmembranesegment and a 92 aa cytoplasmic domain. Consistent with type I cytokinereceptors, the extracellular region contains four positionally conservedcysteine residues, a WSxWS motif (for receptor folding and ligand binding),and three fibronectin type III repeats. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminalSequence : | Gly29 |
Molecular Weight : | 80 kDa |
Activity : | Measuredby its ability to inhibit IL-27-antiviral activity using HepG2 humanhepatocellular carcinoma cells infected with encephalomyocarditis (EMC)virus. Bender H. et al. (2009) Hepatology 50:585. The ED50 forthis effect is typically 2-12 μg/mL. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
SDS-PAGE : | 105-115kDa, reducing conditions |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100 μg/mL in sterile PBS |
Storage : | Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt,-20 to -70°C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Il27ra interleukin 27 receptor,alpha [ Mus musculus ] |
Official Symbol : | Il27ra |
Synonyms : | Il27ra; interleukin27 receptor, alpha; CRL1; Tccr; Wsx1; WSX-1; IL-27R; zcytor1; interleukin-27receptor subunit alpha; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; T cellcytokine receptor; IL-27 receptor subunit alpha; type I T-cell cytokinereceptor; cytokine receptor family, class 1 (WSXWS), member 1 |
Gene ID : | 50931 |
mRNA Refseq : | NM_016671 |
Protein Refseq : | NP_057880 |
UniProt ID : | O70394 |
Chromosome Location : | 8 C3; 8 |
Function : | interleukin-27receptor activity; protein binding; receptor activity |
◆ Recombinant Protein
Il27ra-3519M | Recombinant Mouse Il27ra Protein, Myc/DDK-tagged | +Inquiry |
IL27RA-1928H | Recombinant Human IL27RA Protein, MYC/DDK-tagged | +Inquiry |
IL27RA-5203H | Recombinant Human IL27RA Protein, GST-tagged | +Inquiry |
IL27RA-151H | Recombinant Human IL27RA Protein, DYKDDDDK-tagged | +Inquiry |
Il27RA-782H | Active Recombinant Human Il27RA, MIgG2a Fc-tagged | +Inquiry |
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◆ Lysates
IL27RA-2909HCL | Recombinant Human IL27RA cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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