Recombinant Human IL27RA Protein, GST-tagged
|Product Overview :||Human IL27RA partial ORF ( NP_004834, 33 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.|
- Gene Information
- Related Products
|Description :||In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq|
|Source :||Wheat Germ|
|Molecular Mass :||36.74 kDa|
|AA Sequence :||QGSAGPLQCYGVGPLGDLNCSWEPL GDLGAPSELHLQSQKYRSNKTQTVA VAAGRSWVAIPREQLTMSDKLLVWG TKAGQPLWPPVFVNLETQMKPNAPR|
|Applications :||Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
|Notes :||Best use within three months from the date of receipt of this protein.|
|Storage :||Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.|
|Storage Buffer :||50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.|
|Gene Name :||IL27RA interleukin 27 receptor, alpha [ Homo sapiens ]|
|Official Symbol :||IL27RA|
|Synonyms :||IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R;|
|Gene ID :||9466|
|mRNA Refseq :||NM_004843|
|Protein Refseq :||NP_004834|
|UniProt ID :||Q6UWB1|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.
Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.
It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.
It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.
The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.
No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.
Customer Reviews (3)Write a review
Techniques such as ELISA or flow cytometry can be used to detect IL-27RA concentrations in body fluids or cells. -
Molecular structure of IL-27RA protein was analyzed by crystallography or NMR, and the binding mode and interaction mechanism with IL-27 were revealed. -
The regulation of IL-27RA on cell signal transduction pathway and changes in cell function were evaluated by cell experiments. -
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