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Recombinant Human IL27RA protein, His & T7-tagged

Cat.No. : IL27RA-5788H
Product Overview : Recombinant Human IL27RA aa. (Glu123~Pro343 (Accession # Q6UWB1)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Description : In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 28.2kDa
Protein length : Glu123~Pro343 (Accession # Q6UWB1)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : IL27RA interleukin 27 receptor subunit alpha [ Homo sapiens (human) ]
Official Symbol : IL27RA
Synonyms : CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; T-cell cytokine receptor type 1; class I cytokine receptor; cytokine receptor WSX-1; cytokine receptor-like 1; interleukin 27 receptor, alpha; type I T-cell cytokine receptor; interleukin-27 receptor subunit alpha
Gene ID : 9466
mRNA Refseq : NM_004843.3
Protein Refseq : NP_004834.1
UniProt ID : Q6UWB1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the use of Il27ra? 07/02/2022

In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

What is the action mechanism of Il27ra? 02/10/2022

Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

Does the clinical applications of Il27ra? 09/08/2020

It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

Can Il27ra be used with other drugs? 10/29/2019

It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

Can Il27ra be used in children? 09/27/2019

The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

What are the side effects of Il27ra? 08/19/2019

No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.

Customer Reviews (3)

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Reviews
03/19/2022

    Good stability, stable structure, not easy to deteriorate.

    12/08/2021

      The preparation process is very convenient and suitable for novice operators.

      02/21/2020

        This method is highly sensitive and can detect small amounts of protein.

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