Recombinant Human IL27RA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IL27RA-2622H
• Product Overview: IL27RA MS Standard C13 and N15-labeled recombinant protein (NP_004834) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 69.3 kDa
• AA Sequence: MRGGRGAPFWLWPLPKLALLPLLWV LFQRTRPQGSAGPLQCYGVGPLGDL NCSWEPLGDLGAPSELHLQSQKYRS NKTQTVAVAAGRSWVAIPREQLTMS DKLLVWGTKAGQPLWPPVFVNLETQ MKPNAPRLGPDVDFSEDDPLEATVH WAPPTWPSHKVLICQFHYRRCQEAA WTLLEPELKTIPLTPVEIQDLELAT GYKVYGRCRMEKEEDLWGEWSPILS FQTPPSAPKDVWVSGNLCGTPGGEE PLLLWKAPGPCVQVSYKVWFWVGGR ELSPEGITCCCSLIPSGAEWARVSA VNATSWEPLTNLSLVCLDSASAPRS VAVSSIAGSTELLVTWQPGPGEPLE HVVDWARDGDPLEKLNWVRLPPGNL SALLPGNFTVGVPYRITVTAVSASG LASASSVWGFREELAPLVGPTLWRL QDAPPGTPAIAWGEVPRHQLRGHLT HYTLCAQSGTSPSVCMNVSGNTQSV TLPDLPWGPCELWVTASTIAGQGPP GPILRLHLPDNTLRWKVLPGILFLW GLFLLGCGLSLATSGRCYHLRHKVL PRWVWEKVPDPANSSSGQPHMEQVP EAQPLGDLPILEVEEMEPPPVMESS QPAQATAPLDSGYEKHFLPTPEELG LLGPPRPQVLASGPTRTRRLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IL27RA interleukin 27 receptor subunit alpha [ Homo sapiens (human) ]
• Official Symbol: IL27RA
• Synonyms: IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R
• Gene ID: 9466
• mRNA Refseq: NM_004843
• Protein Refseq: NP_004834
• MIM: 605350
• UniProt ID: Q6UWB1

Reviews

03/19/2022

Good stability, stable structure, not easy to deteriorate.

12/08/2021

The preparation process is very convenient and suitable for novice operators.

02/21/2020

This method is highly sensitive and can detect small amounts of protein.

Q&As

What is the use of Il27ra?

In general, Il27ra should be administered by subcutaneous injection. For specific use, follow your doctor's advice and read the drug label carefully.

What is the action mechanism of Il27ra?

Il27ra regulates the function of immune cells by binding to its receptor, inhibiting inflammatory response and enhancing antiviral ability.

Does the clinical applications of Il27ra?

It is mainly used in clinical treatment of immune-related diseases, such as tumors, autoimmune diseases and so on.

Can Il27ra be used with other drugs?

It can be used in conjunction with other medications in certain cases, but be sure to inform your doctor about the medications you are using to avoid the possibility of drug interactions.

Can Il27ra be used in children?

The use of Il27ra in children is not yet clear, please follow the guidance of your doctor.

What are the side effects of Il27ra?

No significant side effects of recombinant Il27ra have been found, but common adverse reactions such as local reactions and anaphylaxis may occur.