Active Recombinant Human Il27RA, MIgG2a Fc-tagged
Cat.No. : | Il27RA-782H |
Product Overview : | The extracellular domain of human IL-27RA (AAH28003.1) (Gly34-Lys516) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell |
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Species : | Human |
Source : | CHO |
Tag : | Fc |
ProteinLength : | 34-516 a.a. |
Description : | IL27RA (interleukin 27 receptor, alpha) is a protein-coding gene. Diseases associated with IL27RA include membranous glomerulonephritis, and glomerulonephritis, and among its related super-pathways are Th1 Differentiation. GO annotations related to this gene include transmembrane signaling receptor activity and interleukin-27 receptor activity. |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells. |
Molecular Mass : | 78KDa (monomer) |
AA Sequence : | Gly34-Lys516 |
Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name | IL27RA interleukin 27 receptor, alpha [ Homo sapiens ] |
Official Symbol | IL27RA |
Synonyms | IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R; |
Gene ID | 9466 |
mRNA Refseq | NM_004843 |
Protein Refseq | NP_004834 |
MIM | 605350 |
UniProt ID | Q6UWB1 |
Chromosome Location | 19p13.11 |
Pathway | IL27-mediated signaling events, organism-specific biosystem; |
Function | interleukin-27 receptor activity; receptor activity; transmembrane signaling receptor activity; |
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Not For Human Consumption!
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