Recombinant Human IL27RA protein, Fc-tagged

• Cat.No.: IL27RA-018H
• Product Overview: Recombinant Human IL27RA protein (Gln33-Arg514) was fused to human IgG2a Fc tag at the C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
• Source: HEK293
• Species: Human
• Tag: human IgG1 Fc
• Predicted N Terminal: Gln33
• Form: 50 mM Tris, 100 mM Glycine, pH7.5
• Molecular Mass: Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
• Protein length: Gln33-Arg514
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20°C to -70°C for 12 months in lyophilized state;
  -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IL27RA
• Official Symbol: IL27RA
• Synonyms: IL27RA,CRL1,TCCR,WSX1
• Gene ID: 9466
• mRNA Refseq: NM_004843.4
• Protein Refseq: NP_004834.1
• MIM: 605350
• UniProt ID: Q6UWB1