Recombinant Human IL27RA protein, Fc-tagged IL27RA-018H

Recombinant Human IL27RA protein, Fc-tagged

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Recombinant Human IL27RA protein, Fc-tagged

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Cat.No. : IL27RA-018H
Product Overview : Recombinant Human IL27RA protein (Gln33-Arg514) was fused to human IgG2a Fc tag at the C-terminus and expressed in human 293 cells (HEK293).
Description : Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
Source : HEK293
Species : Human
Tag : human IgG1 Fc
Predicted N Terminal : Gln33
Form : 50 mM Tris, 100 mM Glycine, pH7.5
Molecular Mass : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Protein length : Gln33-Arg514
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
SDS-PAGE of IL27RA-018H :

Human IL-27 Ra, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Gene Name : IL27RA
Official Symbol : IL27RA
Synonyms : IL27RA,CRL1,TCCR,WSX1
Gene ID : 9466
mRNA Refseq : NM_004843.4
Protein Refseq : NP_004834.1
MIM : 605350
UniProt ID : Q6UWB1

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