Recombinant Human IL27RA protein, Fc-tagged
Cat.No. : | IL27RA-018H |
Product Overview : | Recombinant Human IL27RA protein (Gln33-Arg514) was fused to human IgG2a Fc tag at the C-terminus and expressed in human 293 cells (HEK293). |
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Species : | Human |
Source : | HEK293 |
Tag : | Fc |
ProteinLength : | Gln33-Arg514 |
Description : | Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms. |
Predicted N Terminal : | Gln33 |
Form : | 50 mM Tris, 100 mM Glycine, pH7.5 |
Molecular Mass : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name | IL27RA |
Official Symbol | IL27RA |
Synonyms | IL27RA,CRL1,TCCR,WSX1 |
Gene ID | 9466 |
mRNA Refseq | NM_004843.4 |
Protein Refseq | NP_004834.1 |
MIM | 605350 |
UniProt ID | Q6UWB1 |
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Not For Human Consumption!
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