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Active GMP Recombinant Mouse Ccl2 Protein, His-Tagged
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Cat.No. : | Ccl2-01M Optional Service: Optional requirements on this protein |
Product Overview : | GMP Recombinant Mouse Ccl2 Protein, His-Tagged was expressed in Escherichia coli cell-derived in an animal component free process under cGMP guidelines. |
Description : | This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to chemoattract BaF3 cells transfected with CCR2A. The ED50 for this effect is <8 ng/mL. |
AA Sequence : | QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN with polyhistidine tag at the N-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Notes : | Please use within one month after protein reconstitution. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Figure : |
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Gene Name : | Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Ccl2 |
Synonyms : | Mip1a; Scya3; G0S19-1; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha |
Gene ID : | 20296 |
mRNA Refseq : | NM_011333.3 |
Protein Refseq : | NP_035463.1 |
UniProt ID : | P10148 |
◆ Recombinant Protein
CCL2-016H | Recombinant Human CCL2 Protein, Biotinylated | +Inquiry |
CCL2-120C | Recombinant Cynomolgus Monkey CCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL2-511R | Recombinant Rhesus Macaque CCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL2-2146C | Recombinant Cattle CCL2 Protein, His-tagged | +Inquiry |
CCL2-11H | Recombinant Human CCL2 Protein, His-tagged | +Inquiry |
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◆ Lysates
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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