Active Recombinant Bovine Interleukin 13
Cat.No. : | IL13-234B |
Product Overview : | Recombinant Bovine IL-13 was expressed inYeast. MW= 12.6 kDa (112 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL13-234B |
Description : | IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. |
Source : | Yeast. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | SPVPSATALK ELIEELVNIT QNQKVPLCNG SMVWSLNLTS SMYCAALDSL ISISNCSVIQ RTKRMLNALC PHKPSAKQVS SEYVRDTKIE VAQFLKDLLR HSRIVFRNER FN. |
Bioactivity : | The biological activity of recombinant bovine IL-13 was measured in a cell proliferation assay using the human TF-1 cell line. The ED50 for this effect is typically 20 - 30 ng/mL. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL13 interleukin 13 [ Bos taurus ] |
Synonyms : | interleukin 13; IL13; interleukin-13; IL-13 |
Gene ID : | 281247 |
mRNA Refseq : | NM_174089.1 |
Protein Refseq : | NP_776514.1 |
UniProt ID : | Q9XSV9 |
Chromosome Location : | 7 |
Pathway : | Asthma; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Jak-STAT signaling pathway |
Function : | cytokine activity; interleukin-13 receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
Il13-144M | Recombinant Active Mouse IL13 Protein, His-tagged(C-ter) | +Inquiry |
IL13-4328Z | Recombinant Zebrafish IL13 Protein | +Inquiry |
IL13-143H | Recombinant Active Human IL13 Protein, His-tagged(C-ter) | +Inquiry |
IL13-255I | Active Recombinant Human IL13 Protein | +Inquiry |
Il13-038I | Active Recombinant Mouse Il13 Protein (111 aa) | +Inquiry |
◆ Lysates | ||
IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
IL13-2922HCL | Recombinant Human IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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