Active Recombinant Canine CA9 Protein, Fc-tagged, Alexa Fluor 555 conjugated
Cat.No. : | CA9-1544CAF555 |
Product Overview : | Alexa Fluor 555 conjugated recombinant canine CA9 (Met1-Leu410) was expressed in human HEK 293 cells and fused with the Fc region of human IgG1 at the C-terminus. |
Availability | July 26, 2024 |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
Source : | HEK293 |
Species : | Dog |
Tag : | Fc |
Form : | Lyophilized Powder |
Bio-activity : | Measured by its esterase activity. The specific activity is > 10 pmoles/min/ μg. |
Molecular Mass : | The recombinant canine CA9/Fc is a disulfide-linked homodimer. The reduced monomer comprises 614 amino acids and has a predicted molecular mass of 67.6 kDa. The apparent molecular mass of the protein is approximately 79 kDa in SDS-PAGE under reducing conditions. |
Protein length : | 614 |
Endotoxin : | < 1.0 EU/ μg protein as determined by the LAL method. |
Purity : | > 99 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 555 via amines With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 25 mM Tris, 0.15 M NaCl, pH 7.5 |
Gene Name : | CA9 carbonic anhydrase 9 [ Canis lupus familiaris (dog) ] |
Official Symbol : | CA9 |
Synonyms : | CA9; carbonic anhydrase 9 |
Gene ID : | 611933 |
mRNA Refseq : | NM_001145174 |
Protein Refseq : | NP_001138646 |
UniProt ID : | E2RAI4 |
Products Types
◆ Recombinant Protein | ||
CA9-0250H | Recombinant Human CA9 Protein, GST-Tagged | +Inquiry |
CA9-2272H | Recombinant Human CA9 Protein, MYC/DDK-tagged | +Inquiry |
Car9-1962M | Recombinant Mouse Car9 Protein, Myc/DDK-tagged | +Inquiry |
CA9-481H | Recombinant Human CA9 Protein, His (Fc)-Avi-tagged | +Inquiry |
CA9-117H | Recombinant Human CA9 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CA9-1447CCL | Recombinant Canine CA9 cell lysate | +Inquiry |
CA9-3065HCL | Recombinant Human CA9 cell lysate | +Inquiry |
CA9-2189MCL | Recombinant Mouse CA9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewExceptional consistency, vital for our research's reliability.
Critical support for our protein analysis and quantification.
Unmatched accuracy in protein identification and sequencing.
Q&As (7)
Ask a questionThe HIF-1 signaling pathway primarily regulates CA9 in response to cellular oxygen levels.
CA9 aids in extracellular acidification, promoting tumor cell survival and invasion in acidic tumor microenvironments.
CA9 expression is upregulated by the hypoxia-inducible factor (HIF) under low oxygen conditions.
Elevated CA9 levels often correlate with poor prognosis in various cancers due to its role in tumor adaptation to hypoxia.
Potential modifications like glycosylation can be identified using techniques like mass spectrometry.
Several inhibitors, like acetazolamide derivatives, have been explored to target CA9 in cancer treatment.
CA9 helps tumors survive in hypoxic conditions by regulating pH through the conversion of CO2 to bicarbonate and protons.
Ask a Question for All CA9 Products
Required fields are marked with *
My Review for All CA9 Products
Required fields are marked with *
Inquiry Basket