Active Recombinant Chicken Insulin-Like Growth Factor 1 (Somatomedin C)

• Cat.No.: IGF1-322C
• Product Overview: Recombinant Chicken Insulin-Like Growth Factor 1 (Somatomedin C) was produced inE. coli.

Specification

• Cat. No.: IGF1-322C
• Description: Chicken Insulin-like Growth Factor1 (Chicken IGF1) is a polypeptide comprising 70 amino acids, eight of which differ from the amino acid sequence of human IGF1. Chicken IGF1 has been shown to stimulate growth in many cell types, including rat L6 myoblasts and chicken embryo fibroblasts, hepatocytes, adipocytes and myoblasts. GroPep’s Receptor Grade chicken IGF1 is a high quality research reagent particularly suited for use in avian cells and in vivo growth studies or for other general research purposes.
• Source: E. coli.
• Purity: >95 % (by HPLC and N-terminal sequence analysis).
• Molecular Weight: 7738 daltons – confirmed by Mass Spectrometry.
• N-terminal Sequence Analysis: 5 residues >95 % single sequence.
• Activity: Type 1 IGF receptor binding assay: ED50 <10 ng/ml. Stimulation of protein synthesis in rat L6 myoblasts: ED₅₀<30 ng/ml.
• Endotoxin: <0.1 EU/µg.
• State And Appearance: Lyophilized white powder. Dried from 0.1 M acetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa).
• Storage: At least 2 years at 2 – 4℃ (lyophilized).

Gene Information

• Gene Name: IGF1 insulin-like growth factor 1 (somatomedin C) [ Gallus gallus ]
• Synonyms: IBP1; IGF-I; IGF-IA; IGFI; MGF; Somatomedin-C; Mechano growth factor; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); somatomedin C; Insulin-like growth factor IB [Precursor]; IGF-IB.
• Gene ID: 418090
• mRNA Refseq: NM_001004384
• Protein Refseq: NP_001004384
• UniProt ID: P18254
• Pathway: Focal adhesion; Progesterone-mediated oocyte maturation; mTOR signaling pathway; p53 signaling pathway
• Function: growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding