Active Recombinant Full Length Human AMACR Protein, C-Flag-tagged
Cat.No. : | AMACR-257HFL |
Product Overview : | Recombinant Full Length Human AMACR Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | ELISA capture for autoantibodies |
Molecular Mass : | 42.2 kDa |
AA Sequence : | MALQGISVMELSGLAPGPFCAMVLA DFGARVVRVDRPGSRYDVSRLGRGK RSLVLDLKQPRGAAVLRRL CKRSDVLLEPFRRGVMEKLQLGPEI LQRENPRLIYARLSGFGQSGSFCRL AGHDINYLALSGVLSKIGR SGENPYAPLNLLADFAGGGLMCALG IIMALFDRTRTDKGQVIDANMVEGT AYLSSFLWKTQKSSLWEAP RGQNMLDGGAPFYTTYRTADGEFMA VGAIEPQFYELLIKGLGLKSDELPN QMSMDDWPEMKKKFADVFA KKTKAEWCQIFDGTDACVTPVLTFE EVVHHDHNKERGSFITSEEQDVSPR PAPLLLNTPAIPSFKRDPF IGEHTEEILEEFGFSREEIYQLNSD KIIESNKVKASLSGPTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Metabolic pathways, Primary bile acid biosynthesis |
Gene Name : | AMACR alpha-methylacyl-CoA racemase [ Homo sapiens (human) ] |
Official Symbol : | AMACR |
Synonyms : | RM; RACE; CBAS4; P504S; AMACRD |
Gene ID : | 23600 |
mRNA Refseq : | NM_014324.6 |
Protein Refseq : | NP_055139.4 |
MIM : | 604489 |
UniProt ID : | Q9UHK6 |
Products Types
◆ Recombinant Protein | ||
AMACR-140R | Recombinant Rhesus Macaque AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-330H | Recombinant Human AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
Amacr-1607M | Recombinant Mouse Amacr Protein, Myc/DDK-tagged | +Inquiry |
AMACR-497M | Recombinant Mouse AMACR Protein, His (Fc)-Avi-tagged | +Inquiry |
AMACR-106H | Recombinant Human AMACR, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
AMACR-8888HCL | Recombinant Human AMACR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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