Active Recombinant Full Length Human ELAVL4 Protein, C-Flag-tagged

• Cat.No.: ELAVL4-197HFL
• Product Overview: Recombinant Full Length Human ELAVL4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3' UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: EMSA reaction
• Molecular Mass: 41.6 kDa
• AA Sequence: MVMIISTMEPQVSNGPTSNTSNGPS SNNRNCPSPMQTGATTDDSKTNLIV NYLPQNMTQEEFRSLFGSIG EIESCKLVRDKITGQSLGYGFVNYI DPKDAEKAINTLNGLRLQTKTIKVS YARPSSASIRDANLYVSGLP KTMTQKELEQLFSQYGRIITSRILV DQVTGVSRGVGFIRFDKRIEAEEAI KGLNGQKPSGATEPITVKFA NNPSQKSSQALLSQLYQSPNRRYPG PLHHQAQRFRLDNLLNMAYGVKRLM SGPVPPSACSPRFSPITIDG MTSLVGMNIPGHTGTGWCIFVYNLS PDSDESVLWQLFGPFGAVNNVKVIR DFNTNKCKGFGFVTMTNYDE
  AAMAIASLNGYRLGDRVLQVSFKTN KAHKSTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: ELAVL4 ELAV like RNA binding protein 4 [ Homo sapiens (human) ]
• Official Symbol: ELAVL4
• Synonyms: HUD; PNEM
• Gene ID: 1996
• mRNA Refseq: NM_021952.5
• Protein Refseq: NP_068771.2
• MIM: 168360
• UniProt ID: P26378