Active Recombinant Full Length Human MMP9 Protein

• Cat.No.: MMP9-01HFL
• Product Overview: Active Recombinant Full Length Human MMP9 Protein was expressed in human neutrophil granulocytes (buffy coat).

Specification

• Species: Human
• Source: Isolated from stimulated human neutrophil granulocytes (buffy coat). Disulfide-bridged MMP-9 homodimer.
• Description: MMP-9 hydrolyzes the extracellular matrix, e.g. collagen types IV, V and IX and gelatin.
• Form: Liquid
• Molecular Mass: ~220 kDa
• Bio-activity: ≥1,400 mU/mg protein. One unit is defined as the amount of enzyme that hydrolyzes 1 μmol Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH per min. at 37 centigrade, pH 7.0.
• Purity: ≥95%
• Storage: Long Term Storage: -80 centigrade
• Storage Buffer: In 50mM Tris-HCl, pH 7.0, containing 200mM sodium chloride, 5mM CaCl2, 1μM ZnCl2, 0.05% BRIJ35, and 0.05% sodium azide.
• Handling: Avoid freeze/thaw cycles.
• Shipping: Dry Ice
• Reference: 1. Progelatinase B forms from human neutrophils. complex formation of monomer/lipocalin with TIMP-1: H. Kolkenbrock, et al.; Biol. Chem. 377, 529 (1996). 2. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases: C.G. Knight, et al.; FEBS Lett. 296, 263 (1992). 3. Synthetic substrates for vertebrate collagenase: Y. Masui, et al.; Biochem. Med. 17, 215 (1977).

Gene Information

• Gene Name: MMP9 matrix metallopeptidase 9 [ Homo sapiens (human) ]
• Official Symbol: MMP9
• Synonyms: MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); CLG4B, matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) , matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase-9; 92 kDa gelatinase; type V collagenase; macrophage gelatinase; 92 kDa type IV collagenase; matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); GELB; CLG4B; MMP-9; MANDP2
• Gene ID: 4318
• mRNA Refseq: NM_004994
• Protein Refseq: NP_004985
• MIM: 120361
• UniProt ID: P14780