Active Recombinant Full Length Human MOV10 Protein, C-Flag-tagged

• Cat.No.: MOV10-378HFL
• Product Overview: Recombinant Full Length Human MOV10 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables 5'-3' RNA helicase activity and RNA binding activity. Involved in defense response to virus; negative regulation of transposition, RNA-mediated; and posttranscriptional regulation of gene expression. Located in P-body and cytosol. Implicated in hypertension.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Binding assay
  In vitro reverse transcription assay
• Molecular Mass: 113.5 kDa
• AA Sequence: MPSKFSCRQLREAGQCFESFLVVRG LDMETDRERLRTIYNRDFKISFGTP APGFSSMLYGMKIANLAYVT KTRVRFFRLDRWADVRFPEKRRMKL GSDISKHHKSLLAKIFYDRAEYLHG KHGVDVEVQGPHEARDGQLL IRLDLNRKEVLTLRLRNGGTQSVTL THLFPLCRTPQFAFYNEDQELPCPL GPGECYELHVHCKTSFVGYF PATVLWELLGPGESGSEGAGTFYIA RFLAAVAHSPLAAQLKPMTPFKRTR ITGNPVVTNRIEEGERPDRA KGYDLELSMALGTYYPPPRLRQLLP MLLQGTSIFTAPKEIAEIKAQLETA LKWRNYEVKLRLLLHLEELQ MEHDIRHYDLESVPMTWDPVDQNPR LLTLEVPGVTESRPSVLRGDHLFAL LSSETHQEDPITYKGFVHKV ELDRVKLSFSMSLLSRFVDGLTFKV NFTFNRQPLRVQHRALELTGRWLLW PMLFPVAPRDVPLLPSDVKL KLYDRSLESNPEQLQAMRHIVTGTT RPAPYIIFGPPGTGKTVTLVEAIKQ VVKHLPKAHILACAPSNSGA DLLCQRLRVHLPSSIYRLLAPSRDI RMVPEDIKPCCNWDAKKGEYVFPAK KKLQEYRVLITTLITAGRLV SAQFPIDHFTHIFIDEAGHCMEPES LVAIAGLMEVKETGDPGGQLVLAGD PRQLGPVLRSPLTQKHGLGY SLLERLLTYNSLYKKGPDGYDPQFI TKLLRNYRSHPTILDIPNQLYYEGE LQACADVVDRERFCRWAGLP RQGFPIIFHGVMGKDEREGNSPSFF NPEEAATVTSYLKLLLAPSSKKGKA RLSPRSVGVISPYRKQVEKI RYCITKLDRELRGLDDIKDLKVGSV EEFQGQERSVILISTVRSSQSFVQL DLDFNLGFLKNPKRFNVAVT RAKALLIIVGNPLLLGHDPDWKVFL EFCKENGGYTGCPFPAKLDLQQGQN LLQGLSKLSPSTSGPHSHDY
  LPQEREGEGGLSLQVEPEWRNELTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: MOV10 Mov10 RISC complex RNA helicase [ Homo sapiens (human) ]
• Official Symbol: MOV10
• Synonyms: gb110; fSAP113
• Gene ID: 4343
• mRNA Refseq: NM_020963.5
• Protein Refseq: NP_066014.1
• MIM: 610742
• UniProt ID: Q9HCE1