Active Recombinant Human AKR1C4

• Cat.No.: AKR1C4-721H
• Product Overview: Recombinant Human AKR1C4 (Accession # NP_001809) Met1-Tyr323 was produced in E. coli-derived.

Specification

• Source: E. coli
• Species: Human
• Predicted N Terminal: Met1
• Form: Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.
• Bio-activity: Measured by its NADP+-dependent oxidation of cholic acid.The specific activity is >300 pmol/min/µg, as measured under the described conditions.
• Molecular Mass: Recombinant Human AKR1C4 has a calculated MW of 37 kDa. In SDS-PAGE migrates as 36-38 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: AKR1C4 aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) [ Homo sapiens ]
• Official Symbol: AKR1C4
• Synonyms: AKR1C4; aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4); CHDR; aldo-keto reductase family 1 member C4; 3 alpha HSD; C11; CDR; DD4; HAKRA; MGC22581; 3-alpha-HSD1; dihydrodiol dehydrogenase isozyme DD4; type I 3-alpha-hydroxysteroid dehydrogenase; DD-4; 3-alpha-HSD
• Gene ID: 1109
• mRNA Refseq: NM_001818
• Protein Refseq: NP_001809
• MIM: 600451
• UniProt ID: P17516
• Chromosome Location: 10p15.1