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Active Recombinant Human BMP2 Protein

Cat.No. : BMP2-011H
Product Overview : The mature recombinant human BMP-2 protein consists of 114 amino acids (283-396) without tag was expressed in E. coli.
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Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Source : E. coli
Species : Human
Bio-activity : Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 40-200 ng/mL.
Molecular Mass : 13 kDa
Product-Related Proteins : 283-396
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]
Official Symbol : BMP2
Synonyms : BMP2; bone morphogenetic protein 2; BDA2; BMP2A; SSFSC; SSFSC1; bone morphogenetic protein 2; bone morphogenetic protein 2A
Gene ID : 650
mRNA Refseq : NM_001200
Protein Refseq : NP_001191
MIM : 112261
UniProt ID : P12643

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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05/06/2023

    We have tested the recombinant protein in our ELISAs and it performs well.

    02/01/2023

      I'm pleased with your recombinant products. It is done well in our experiment.

      01/29/2023

        Very nice puchase experience with all of you.

        08/06/2022

          I’ve used the products you provided, and they all work good in my study.

          04/09/2021

            Thanks so much! Your protein performed really well,

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