Active Recombinant Human BMP8A Protein

• Cat.No.: BMP8A-017H
• Product Overview: The mature recombinant human BMP-8a protein consists of 139 amino acids (264-402) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 264-402 a.a.
• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human BMP-8a is present at 1 μg/mL, the concentration of recombinant human BMPR-1A Fc Chimera that produces 50% of the optimal binding response is approximately 1.5-6 μg/mL.
• Molecular Mass: 16 kDa
• Product-Related Proteins: 264-402
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: BMP8A bone morphogenetic protein 8a [ Homo sapiens (human) ]
• Official Symbol: BMP8A
• Synonyms: BMP8A; bone morphogenetic protein 8a; OP-2; bone morphogenetic protein 8A; Names; BMP-8A
• Gene ID: 353500
• mRNA Refseq: NM_181809
• Protein Refseq: NP_861525
• UniProt ID: Q7Z5Y6