Active Recombinant Human Calprotectin Protein

Cat.No. : S100A8-1013H
Product Overview : Recombinant Human calprotectin heterotetramer (S100A8/S100A9) protein with an Nterminal histidine tag in the S100A8 subunit. Predicted molecular weights: S100A8 12 kDa, S100A9 13 kDa.
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Description : Calprotectin belongs to the family of S100 proteins and is composed of two subunits S100A8 and S100A9. Increased plasma concentrations are found in response to infections and inflammation. Faecal calprotectin measurement is used for detection of gastrointestinal inflammation or neoplasia and for assessment of inflammatory bowel disease activity and response to treatment
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized from 0.2 μm filtered solution
Bio-activity : Anti-h Calprotectin 3403: + Anti-h Calprotectin 3404: + Anti-h Calprotectin 3405: + Anti-h Calprotectin 3406: + Anti-h Calprotectin 3407: +
Molecular Mass : S100A8 12 kDa, S100A9 13 kDa
Storage : 2–8centigrade
Concentration : 0.5 mg/ml when reconstituted with 200 µl of deionized water
Storage Buffer : 20 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, pH 8.0; containing 6 % sucrose as a stabilize
Reconstitution : Reconstitute lyophilized protein with 200 µl of deionized water
Gene Name : S100A8 S100 calcium binding protein A8 [ Homo sapiens ]
Official Symbol : S100A8
Synonyms : S100A8; S100 calcium binding protein A8; CAGA, CFAG, S100 calcium binding protein A8 (calgranulin A) , S100 calcium binding protein A8 (calgranulin A); protein S100-A8; 60B8AG; CGLA; MRP8; P8; MRP-8; calgranulin A; calgranulin-A; cystic fibrosis antigen; calprotectin L1L subunit; urinary stone protein band A; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; S100 calcium-binding protein A8 (calgranulin A); MIF; NIF; CAGA; CFAG; L1Ag; CP-10; MA387;
Gene ID : 6279
mRNA Refseq : NM_002964
Protein Refseq : NP_002955
MIM : 123885
UniProt ID : P05109

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do alterations in S100A8 expression impact cellular stress responses and aging? 03/03/2022

Changes in S100A8 expression impact cellular stress responses, with implications for aging and age-related diseases.

How does S100A8 contribute to the pathogenesis of cancer, especially in terms of tumor growth and metastasis? 12/12/2021

S100A8 contributes to cancer development, influencing tumor cell proliferation and metastatic potential.

What is the impact of S100A8 on wound healing and tissue repair mechanisms? 03/02/2021

S100A8 is involved in wound healing, affecting tissue repair and regeneration.

How does S100A8 interact with calcium ions and what are the implications for inflammatory processes? 01/18/2021

S100A8 binds calcium ions, modulating inflammatory processes and cytokine production.

How does S100A8 influence the development and progression of cardiovascular diseases? 11/01/2019

S100A8 affects cardiovascular disease development, impacting inflammation and vascular integrity.

What role does S100A8 play in the immune response, particularly in autoimmune diseases? 09/22/2019

S100A8 plays a significant role in the immune response, impacting the pathogenesis of autoimmune diseases.

What are the effects of S100A8 on skin homeostasis and the development of skin disorders? 10/06/2018

S100A8 influences skin health, playing a role in maintaining skin barrier function and in skin disorders.

Customer Reviews (3)

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Reviews
02/01/2022

    Dependable protein quantification, ensures experimental accuracy.

    10/29/2020

      Consistent western blot results, a lab essential.

      03/12/2020

        Expert protein engineering support, essential for our projects.

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