Active Recombinant Human CCL3 CCL3-15H

Active Recombinant Human CCL3


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Active Recombinant Human CCL3

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Cat.No. : CCL3-15H Optional Service: Optional requirements on this protein
Product Overview : Human recombinant MIP-1 alpha is produced in genetically engineered yeast, and purified by sequential chromatography.
Description : Macrophage Inflammatory Protein MIP-1 alpha is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1 alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1 alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1 alpha is composed of 69 amino acid residues with not possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1 alpha is 60% homologous with human MIP-1 alpha, 75% homologous with murine MIP-1 alpha, and has been shown to be active on murine cells.
Source : yeast
Species : Human
Form : In water at a concentration of 1.0 mg protein/ml
Bio-activity : The biological activity of recombinant human MIP-1 alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.
Molecular Mass : 8 KDa
Purity : Over 95% pure by SDS gel electrophoresis, with low level of endotoxin.
Stability : Several months at -80°C.
Storage : Store at -80°C.
Gene Name : CCL3 chemokine (C-C motif) ligand 3 [ Homo sapiens (human) ]
Official Symbol : CCL3
Synonyms : CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha; C-C motif chemokine 3; SIS-beta; PAT 464.1; G0/G1 switch regulatory protein 19-1; macrophage inflammatory protein 1-alpha;tonsillar lymphocyte LD78 alpha protein;small inducible cytokine A3 (homologous to mouse Mip-1a)
Gene ID : 6348
mRNA Refseq : NM_002983
Protein Refseq : NP_002974
MIM : 182283
UniProt ID : P10147
Chromosome Location : 17q12
Pathway : Chagas disease (American trypanosomiasis); Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Function : CCR1 chemokine receptor binding; calcium-dependent protein kinase C activity; identical protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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