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Active Recombinant Human CCL3
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Cat.No. : | CCL3-15H Optional Service: Optional requirements on this protein |
Product Overview : | Human recombinant MIP-1 alpha is produced in genetically engineered yeast, and purified by sequential chromatography. |
Description : | Macrophage Inflammatory Protein MIP-1 alpha is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1 alpha affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1 alpha also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1 alpha is composed of 69 amino acid residues with not possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1 alpha is 60% homologous with human MIP-1 alpha, 75% homologous with murine MIP-1 alpha, and has been shown to be active on murine cells. |
Source : | yeast |
Species : | Human |
Form : | In water at a concentration of 1.0 mg protein/ml |
Bio-activity : | The biological activity of recombinant human MIP-1 alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis. |
Molecular Mass : | 8 KDa |
Purity : | Over 95% pure by SDS gel electrophoresis, with low level of endotoxin. |
Stability : | Several months at -80°C. |
Storage : | Store at -80°C. |
Gene Name : | CCL3 chemokine (C-C motif) ligand 3 [ Homo sapiens (human) ] |
Official Symbol : | CCL3 |
Synonyms : | CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha; C-C motif chemokine 3; SIS-beta; PAT 464.1; G0/G1 switch regulatory protein 19-1; macrophage inflammatory protein 1-alpha;tonsillar lymphocyte LD78 alpha protein;small inducible cytokine A3 (homologous to mouse Mip-1a) |
Gene ID : | 6348 |
mRNA Refseq : | NM_002983 |
Protein Refseq : | NP_002974 |
MIM : | 182283 |
UniProt ID : | P10147 |
Chromosome Location : | 17q12 |
Pathway : | Chagas disease (American trypanosomiasis); Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Function : | CCR1 chemokine receptor binding; calcium-dependent protein kinase C activity; identical protein binding |
◆ Recombinant Protein
CCL3-0637H | Recombinant Human CCL3 Protein, GST-Tagged | +Inquiry |
CCL3-871R | Recombinant Rat CCL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ccl3-2977M | Recombinant Mouse Ccl3 Protein | +Inquiry |
CCL3-24R | Recombinant Rat CCL3 Protein | +Inquiry |
Ccl3-2037M | Recombinant Mouse Ccl3 Protein | +Inquiry |
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◆ Lysates
CCL3-7723HCL | Recombinant Human CCL3 293 Cell Lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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