Active Recombinant Human CD274 protein, mFc-tagged

• Cat.No.: CD274-2185H
• Product Overview: Active Recombinant Human CD274 protein(Q9NZQ7) is produced by our Mammalian expression system and the target gene encoding Phe19-Thr239 is expressed with a mouse IgG1 Fc tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: mFc
• Protein Length: 19-239 aa
• Form: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Bio-activity: Immobilized Human PD-L1-mFc(CM06) at 2μg/ml (100 μl/well)can bind Anti-Human PDL1 mAb-Fc(NC014).The ED50 of Anti-Human PDL1 mAb-Fc(NC014) is 4.09 ng/ml.
• Molecular Mass: 50.9 Kda
• Endotoxin: < 1 EU/µg as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
• Reconstitution: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: CD274 CD274 molecule [ Homo sapiens ]
• Official Symbol: CD274
• Synonyms: CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296
• Gene ID: 29126
• mRNA Refseq: NM_014143
• Protein Refseq: NP_054862
• MIM: 605402
• UniProt ID: Q9NZQ7