Active Recombinant Human CDC25C, GST-tagged
Cat.No. : | CDC25C-1513H |
Product Overview : | Full-length recombinant human CDC25C was expressed in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | CDC25C (also known as cell division cycle 25 homolog C) is a member of the CDC25 phosphatase family. CDC25C is highly conserved during evolution and it plays a key role in the regulation of cell division. CDC25C activates the partially purified p34 (cdc2)/cyclin B complex and directs the dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. CDC25C also suppresses p53-induced growth arrest. The regulation of CDC25B phosphorylation by p38 is a critical event for initiating the G2/M checkpoint after ultraviolet radiation. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 22 nmol/min/mg |
Molecular Mass : | ~84 kDa |
Protein length : | Full length |
Purity : | >70% |
Applications : | Phosphatase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | CDC25C cell division cycle 25 homolog C (S. pombe) [ Homo sapiens ] |
Official Symbol : | CDC25C |
Synonyms : | CDC25C; cell division cycle 25 homolog C (S. pombe); CDC25, cell division cycle 25 homolog C (S. cerevisiae) , cell division cycle 25C; M-phase inducer phosphatase 3; PPP1R60; protein phosphatase 1; regulatory subunit 60; mitosis inducer CDC25; cell division cycle 25C; phosphotyrosine phosphatase; dual specificity phosphatase CDC25C; protein phosphatase 1, regulatory subunit 60; CDC25; |
Gene ID : | 995 |
mRNA Refseq : | NM_001790 |
Protein Refseq : | NP_001781 |
MIM : | 157680 |
UniProt ID : | P30307 |
Chromosome Location : | 5q31 |
Pathway : | Activation of ATR in response to replication stress, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; |
Function : | WW domain binding; hydrolase activity; protein binding; protein kinase binding; protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
Cdc25c-853M | Recombinant Mouse Cdc25c Protein, MYC/DDK-tagged | +Inquiry |
CDC25C-1480M | Recombinant Mouse CDC25C Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC25C-0918H | Recombinant Human CDC25C Protein, GST-Tagged | +Inquiry |
CDC25C-699H | Recombinant Human Cell Division Cycle 25 Homolog C (S. Pombe) | +Inquiry |
CDC25C-3133M | Recombinant Mouse CDC25C Protein | +Inquiry |
◆ Lysates | ||
CDC25C-7664HCL | Recombinant Human CDC25C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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