Active Recombinant Human FAP Protein, hFc-tagged
Cat.No. : | FAP-372H |
Product Overview : | Recombinant Human FAP Protein(Q12884-1)(Leu26-Asp760) is expressed from Expi293 with hFc tag at the N-terminal. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | hFc |
Form : | Supplied as 0.22μm filtered solution in PBS (pH 7.4). Please dilute to the desired concentration according to the concentration of the solution shown on the product label. |
Bio-activity : | Immobilized Human FAP, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-FAP Antibody, hFc Tag with the EC50 of 0.15μg/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 112.3 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on Tris-Bis PAGE result. |
Protein length : | Leu26-Asp760 |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE > 95% as determined by HPLC |
Storage : | Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | FAP fibroblast activation protein, alpha [ Homo sapiens ] |
Official Symbol : | FAP |
Synonyms : | FAP; fibroblast activation protein, alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA; DKFZp686G13158; |
Gene ID : | 2191 |
mRNA Refseq : | NM_004460 |
Protein Refseq : | NP_004451 |
MIM : | 600403 |
UniProt ID : | Q12884 |
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◆ Lysates | ||
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◆ Assay kits | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFAP can suppress the immune response by modulating the activity of certain immune cells, creating an immunosuppressive tumor microenvironment.
High levels of FAP expression in tumors have been associated with poor prognosis, making it a potential prognostic marker for certain cancers.
Yes, several clinical trials are investigating the safety and efficacy of FAP-targeted therapies in various cancer types.
FAP-targeted therapies are being explored for conditions such as fibrotic diseases and rheumatoid arthritis, extending its potential clinical applications.
Molecular imaging techniques, such as positron emission tomography (PET), can be employed to visualize FAP expression in tumors noninvasively.
Customer Reviews (3)
Write a reviewIt enables accurate detection and quantification of FAP protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.
FAP protein is highly recommended for researchers due to its excellent performance in various assays, particularly in Western blotting (WB) experiments, and its applicability in protein electron microscopy structure analysis.
FAP protein is highly recommended for researchers, as it demonstrates excellent performance in WB experiments and has proven useful in protein electron microscopy structure analysis.
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