Active Recombinant Human FGF3 Protein

Cat.No. : FGF3-037H
Product Overview : The mature recombinant human FGF-3 protein consists of 185 amino acids (28-212) without tag was expressed in E. coli.
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Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using NR6R­3T3 mouse fibroblast cells. The ED50 for this effect is 0.02-0.1 μg/mL in the presence of 1 μg/mL of heparin.
Molecular Mass : 21 kDa
Product-Related Proteins : 28-212
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : FGF3 fibroblast growth factor 3 [ Homo sapiens (human) ]
Official Symbol : FGF3
Synonyms : FGF3; fibroblast growth factor 3; INT2; HBGF-3; fibroblast growth factor 3; FGF-3; INT-2 proto-oncogene protein; V-INT2 murine mammary tumor virus integration site oncogene homolog; fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog); heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; oncogene INT2; proto-oncogene Int-2
Gene ID : 2248
mRNA Refseq : NM_005247
Protein Refseq : NP_005238
MIM : 164950
UniProt ID : P11487

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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