Active Recombinant Human FGF4 Protein

Cat.No. : FGF4-520H
Product Overview : Recombinant Human FGF4 Protein was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Source : E. coli
Species : Human
Form : 20 mM PBS, pH7.4, 5%Trehalose
Bio-activity : The biological activity was determined by the does-dependent stimulation of thymidine uptake by BaF3 cells expressing KGF receptors yielding an ED50 <0.5ng/ml.
Molecular Mass : 19.8 kDa
Endotoxin : Less than 1EU/mg of rHuFGF-4 as determined by LAL method.
Purity : >95% as determined by SDS-PAGE
Storage : This lyophilized preparation is stable at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apportion the reconstituted preparation into sterile distilled water or working aliquots with 20% glycerol or 0.1% BSA and store at -20 centigrade to -70 centigrade. Avoid repeated freeze/thaw cycles.
Reconstitution : Reconstitute in sterile distilled water or aqueous buffer containing 20% glycerol or 0.1% BSA to a concentration of 0.1-1.0mg/mL. Stock solutions should be apportioned into working aliquots and stored at -20 centigrade to -70 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : FGF4 fibroblast growth factor 4 [ Homo sapiens (human) ]
Official Symbol : FGF4
Synonyms : HST; KFGF; FGF-4; HST-1; HSTF1; K-FGF; HBGF-4; HSTF-1
Gene ID : 2249
mRNA Refseq : NM_002007.4
Protein Refseq : NP_001998.1
MIM : 164980
UniProt ID : P08620

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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