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Active Recombinant Human FURIN protein, His-tagged

Cat.No. : FURIN-16H
Product Overview : Recombinant Human FURIN(Asp108-Glu715) fused with His tag at C-terminal was expressed in NS0.
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Source : Mammalian cells
Species : Human
Tag : His
Predicted N Terminal : Asp108 & Asp131
Form : Supplied as a 0.2 μm filtered solution in Tris, CaCl2, NaCl, Brij-35 and Glycerol.
Bio-activity : Measured by its ability to cleave the fluorogenic peptide substrate pERTKR-AMC. The specific activity is >125 pmol/min/µg.
Molecular Mass : Predicted Molecular Mass: 67 kDa;
SDS-PAGE: 65-85 kDa, reducing conditions.
Endotoxin : <1.0 EU per 1 μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
3 months, -20 to -70 centigrade under sterile conditions after opening.
Protein length : Asp108-Glu715
Gene Name : FURIN furin (paired basic amino acid cleaving enzyme) [ Homo sapiens ]
Official Symbol : FURIN
Synonyms : FURIN; furin (paired basic amino acid cleaving enzyme); FUR, PACE, paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) , PCSK3; furin; SPC1; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furin, membrane associated receptor protein; proprotein convertase subtilisin/kexin type 3; paired basic amino acid residue-cleaving enzyme; FUR; PACE; PCSK3;
Gene ID : 5045
mRNA Refseq : NM_002569
Protein Refseq : NP_002560
MIM : 136950
UniProt ID : P09958
Chromosome Location : 15q26.1
Pathway : Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Gamma-carboxylation, transport, and amino-terminal cleavage of proteins, organism-specific biosystem; Glypican 3 network, organism-specific biosystem;
Function : endopeptidase activity; metal ion binding; nerve growth factor binding; peptidase activity; peptide binding; protease binding; serine-type endopeptidase activity; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity;

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
10/10/2022

    The proteins purchased from your company are of very high quality and are suitable for WB experiments.

    02/04/2022

      High quality product at a good price, a satisfactory shopping experience.

      03/30/2021

        The staff were enthusiastic and proactive in communicating with me and solving many technical problems in a timely manner.

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