Active Recombinant Human ICOS, Fc-His tagged
Cat.No. : | ICOS-3243H |
Product Overview : | Recombinant Human ICOS (NP_036224.1) extracellular domain (Met 1-Phe 141), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc-His |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Immobilized Recombinant Human ICOS Ligand / B7-H2 / ICOSLG Protein (Fc Tag) at 2 μg/ml (100 μl/well) can bind Recombinant Human ICOS / AILIM / CD278 Protein (His & Fc Tag),The EC50 is 8-30 ng/mL. |
Molecular Mass : | The recombinant human ICOS/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 368 amino acids and predicts a molecular mass of 41.6 kDa. The apparent molecular mass of rhICOS/Fc monomer is approximately 50 kDa due to glycosylation. |
Protein Length : | Met 1-Phe 141 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | ICOS inducible T-cell co-stimulator [ Homo sapiens ] |
Official Symbol : | ICOS |
Synonyms : | ICOS; inducible T-cell co-stimulator; inducible T-cell costimulator; activation inducible lymphocyte immunomediatory molecule; AILIM; CD278; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; CVID1; MGC39850; |
Gene ID : | 29851 |
mRNA Refseq : | NM_012092 |
Protein Refseq : | NP_036224 |
MIM : | 604558 |
UniProt ID : | Q9Y6W8 |
Products Types
◆ Recombinant Protein | ||
ICOS-2008R | Recombinant Rhesus Macaque ICOS Protein, His (Fc)-Avi-tagged | +Inquiry |
ICOS-672H | Recombinant Human ICOS Protein, Fc-tagged | +Inquiry |
ICOS-055H | Recombinant Human ICOS Protein, His-tagged | +Inquiry |
ICOS-1248M | Acitve Recombinant Mouse ICOS protein(Met1-Gln135), His-tagged | +Inquiry |
ICOS-827M | Active Recombinant Mouse ICOS protein(Met1-Leu144), rFc-tagged | +Inquiry |
◆ Lysates | ||
ICOS-1724MCL | Recombinant Mouse ICOS cell lysate | +Inquiry |
ICOS-2444HCL | Recombinant Human ICOS cell lysate | +Inquiry |
ICOS-1195RCL | Recombinant Rat ICOS cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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