Active Recombinant Human ICOSLG, Fc-tagged, Biotinylated
Cat.No. : | ICOSLG-541H |
Product Overview : | The recombinant human B7-H2/ICOSL/CD275-Fc fusion protein is expressed as a 466 amino acid protein consisting of Asp19 - Thr256 region of B7-H2 (UniProt accession #O75144) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds human ICOS and stimulates human T cell proliferation in the presence of anti-CD3. |
Molecular Mass : | Calculated molecular mass 52 kDa; estimated by SDS-PAGE under reducing condition ~75 kDa probably due to glycosylation. |
AA Sequence : | DTQEKEVRAMVGSDVELSCACPEGS RFDLNDVYVYWQTSESKTVVTYHIP QNSSLENVDSRYRNRALMSPAGMLR GDFSLRLFNVTPQDEQKFHCLVLSQ SLGFQEVLSVEVTLHVAANFSVPVV SAPHSPSQDELTFTCTSINGYPRP NVYWINKTDNSLLDQALQNDTVFLN MRGLYDVVSVLRIARTPSVNIGCCI ENVLLQQNLTVGSQTGNDIGERDK ITENPVSTGEKNAATSTGTHTCPPC PAPELLGGPSVFLFPPKPKDTLMIS RTPEVTCVVVDVSHEDPEVKFNWY VDGVEVHNAKTKPREEQYNSTYRVV SVLTVLHQDWLNGKEYKCKVSNKAL PAPIEKTISKAKGQPREPQVYTLP PSREEMTKNQVSLTCLVKGFYPSDI AVEWESNGQPENNYKTTPPVLDSDG SFFLYSKLTVDKSRWQQGNVFSCS VMHEALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | ICOSLG inducible T-cell co-stimulator ligand [ Homo sapiens ] |
Official Symbol : | ICOSLG |
Synonyms : | ICOSLG; inducible T-cell co-stimulator ligand; ICOSL; ICOS ligand; B7 homolog 2; B7 homologue 2; B7 H2; B7 related protein 1; B7H2; B7RP 1; B7RP1; CD275; GL50; ICOS L; KIAA0653; B7-like protein Gl50; B7-related protein 1; transmembrane protein B7-H2 ICOS ligand; B7-H2; LICOS; B7RP-1; ICOS-L; |
Gene ID : | 23308 |
mRNA Refseq : | NM_015259 |
Protein Refseq : | NP_056074 |
MIM : | 605717 |
UniProt ID : | O75144 |
Chromosome Location : | 21q22.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; |
Function : | receptor binding; |
Products Types
◆ Recombinant Protein | ||
ICOSLG-90H | Recombinant Human ICOSLG Protein, His (Fc)-Avi-tagged | +Inquiry |
ICOSLG-039H | Recombinant Human ICOSLG Protein, His-tagged | +Inquiry |
ICOSLG-794H | Recombinant Human ICOSLG Protein, MYC/DDK-tagged | +Inquiry |
ICOSLG-598H | Recombinant Human ICOSLG Protein | +Inquiry |
ICOSLG-053H | Active Recombinant Human ICOSLG protein, Fc/Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
ICOSLG-1095HCL | Recombinant Human ICOSLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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