Active Recombinant Human IL16 protein
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Cat.No. : | IL16-126H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human IL16 was expressed in E. coli. |
Description : | Interleukin 16 (IL16) is a pleiotrophic cytokine derived from CD8+ T-cells that stimulates chemotaxis in CD4+ lymphocytes, monocytes, and eosinophils. It primes CD4+ T-cells for IL2 and IL15 responsiveness, induces T-lymphocyte Interleukin 2 (IL2) receptor expression, and inhibits HIV replication. The signalling process of IL16 is mediated by CD4, and undergoes proteolysis to yield two functional proteins. IL16 isoform 1 has the possible function of acting as a scaffolding protein to anchor ion channels in the membrane, while isoform 3 is involved in cell cycle progression in T-cells and transcriptional regulation of SKP2. IL16 mRNA expression levels have been found in various tissues such as spleen, bone marrow, thymus, and lymph nodes. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : | The ED50 is 7.5-37.5 ng/mL as determined by its ability to chemoattract human CD4+ T lymphocytes (at a concentration range of 1.0-100.0 ng/mL). |
Molecular Mass : | 13.5 kDa |
Endotoxin : | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
Purity : | >95% |
Applications : | Cell Assay |
Storage : | The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade - 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Reconstitution : | Reconstitute in sterile PBS at 5 μg/Ml |
Figure : |
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Gene Name : | IL16 interleukin 16 [ Homo sapiens ] |
Official Symbol : | IL16 |
Synonyms : | IL16; interleukin 16; interleukin 16 (lymphocyte chemoattractant factor); pro-interleukin-16; FLJ16806; FLJ42735; HsT19289; IL 16; LCF; lymphocyte chemoattractant factor; prIL 16; prointerleukin 16; neuronal interleukin 16; NIL16; PRIL16; prIL-16; FLJ44234; |
Gene ID : | 3603 |
mRNA Refseq : | NM_001172128 |
Protein Refseq : | NP_001165599 |
MIM : | 603035 |
UniProt ID : | Q14005 |
Chromosome Location : | 15q26.3 |
Function : | cytokine activity; |
◆ Recombinant Protein
IL16-2055R | Recombinant Rhesus Macaque IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il16-1239M | Recombinant Mouse Il16 Protein, MYC/DDK-tagged | +Inquiry |
IL16-3143H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL16-1007C | Recombinant Chicken IL16 Protein, His-tagged | +Inquiry |
IL16-1165H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Native Protein
IL16-29736TH | Native Human IL16 | +Inquiry |
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◆ Lysates
IL16-5245HCL | Recombinant Human IL16 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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