Active Recombinant Human IL18BP, Fc Chimera

• Cat.No.: IL18BP-264H
• Product Overview: Recombinant Human IL18BP (Accession # AAD17190) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc Chimera
• Predicted N Terminal: Thr29
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit the IL-18-induced response of KG-1 human acute myelogenous leukemia cells.The ED50 for this effect is typically 0.02 - 0.12 µg/mL in the presence of 40 ng/mL of rhIL-18.
• Molecular Mass: Recombinant Human IL18BP, Fc Chimera has a calculated MW of 44.2 kDa (monomer). In SDS-PAGE migrates as 60-80 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: IL18BP interleukin 18 binding protein [ Homo sapiens ]
• Official Symbol: IL18BP
• Synonyms: IL18BP; interleukin 18 binding protein; interleukin-18-binding protein; IL18BPa; MC51L 53L 54L homolog gene product; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product
• Gene ID: 10068
• mRNA Refseq: NM_001039659
• Protein Refseq: NP_001034748
• MIM: 604113
• UniProt ID: O95998
• Chromosome Location: 11q13