Species : |
Human |
Source : |
Human Cells |
Description : |
IL-2 belongs to the IL-2 protein family. IL-2 is a 15 kDa glycosylated monomer. IL-2 is produced primarily by activated CD4+ T cells, but it is also expressed by naive CD8+ T cells, eosinophils, dendritic, and thymic cells. IL-2 is an essential activator of the immune response, it is required for the growth of T cells, activated B cells and T helper cell differentiation. IL-2 stimulates the activity of NK cells and is involved in anti-inflammatory reactions and in hematopoiesis. |
Bio-activity : |
The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell line). |
Molecular Mass : |
~15 kDa |
Endotoxin : |
<0.5 EU/ μg |
Purity : |
High Purity, >95% by SDS-PAGE |
Stability : |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution. |
Storage Buffer : |
Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein |
Reconstitution : |
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |