Active Recombinant Human IL22 protein, His & Avi-tagged

Cat.No. : IL22-1025H
Product Overview : Recombinant Human IL22 protein(Ala 34 - Ile 179), fused with His tag abd Avi tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : His & Avi
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.
Bio-activity : Immobilized Biotinylated Human IL-22, His,Avitag at 1 μg/mL (100 μL/well)on streptavidin precoated (0.5 μg/well) plate. can bind Human IL-22 Antibody with a linear range of 0.1-4 ng/mL.
Molecular Mass : 20.3 kDa
Protein length : Ala 34 - Ile 179
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL22 interleukin 22 [ Homo sapiens ]
Official Symbol : IL22
Synonyms : IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23;
Gene ID : 50616
mRNA Refseq : NM_020525
Protein Refseq : NP_065386
MIM : 605330
UniProt ID : Q9GZX6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is IL22's role in gut epithelial repair? 02/05/2022

IL22 enhances gut epithelial repair mechanisms.

What are the downstream targets of IL22 signaling? 12/27/2021

IL22 activates STAT3 to modulate downstream targets.

How does IL22 interact with other cytokines in inflammation? 10/06/2021

IL22 interacts synergistically with IL-17 during inflammation.

Is IL22 involved in the pathogenesis of autoimmune diseases? 06/25/2021

IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.

Does IL22 have a role in metabolic syndrome? 02/23/2021

IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.

How is IL22 expression regulated in psoriasis? 09/05/2018

IL22 expression is upregulated in psoriasis.

Does IL22 expression change during viral infections? 07/26/2018

IL22 expression is upregulated during viral infections like Hepatitis C.

Does IL22 contribute to anti-tumor immunity? 03/14/2018

IL22 contributes to anti-tumor immunity by activating NK cells.

How does IL22 modulate T-cell differentiation? 10/30/2017

IL22 promotes Th22 cell differentiation.

What impact do IL22 polymorphisms have on its function? 09/25/2017

IL22 polymorphisms affect its binding affinity and signaling.

Customer Reviews (3)

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Reviews
04/07/2021

    High specificity. -

    03/29/2021

      Good for Th17 differentiation. -

      07/07/2016

        Effective in gut repair assays. -

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