Active Recombinant Human IL22RA1 Protein, His-tagged

• Cat.No.: IL22RA1-735H
• Product Overview: Recombinant Human IL22RA1 (Accession # NP_067081) Pro18-Thr228, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Protein Length: Pro18-Thr228
• Predicted N Terminal: Pro18
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells.The ED50 for this effect is typically 1 - 4 µg/mL in the presence of 1 ng/mL of rhIL-22.
• Molecular Mass: Recombinant Human IL22RA1, His-tagged has a calculated MW of 24.9 kDa. In SDS-PAGE migrates as 34-38 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ]
• Official Symbol: IL22RA1
• Synonyms: IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1
• Gene ID: 58985
• mRNA Refseq: NM_021258
• Protein Refseq: NP_067081
• MIM: 605457
• UniProt ID: Q8N6P7
• Chromosome Location: 1p36.11