Recombinant Canine IL22RA1, Fc tagged

Cat.No. : IL22RA1-102C
Product Overview : Recombinant Canine IL22RA1 (XP_855113.2) (Met1-Thr226), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell.
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Source : Human Cell
Species : Canine
Tag : Fc
Predicted N Terminal : Ala 15
Form : Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant canine IL22RA1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 453 amino acids and has a predicted molecular mass of 51.2 kDa. The apparent molecular mass of the protein is approximately 56 kDa in SDS-PAGE under reducing
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : IL22RA1?interleukin 22 receptor, alpha 1 [?Canis lupus familiaris(dog) ]
Official Symbol : IL22RA1
Gene ID : 612279
mRNA Refseq : XM_850020
Protein Refseq : XP_855113
Chromosome Location : 2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What post-translational modifications occur on IL22RA1? 11/18/2022

IL22RA1 undergoes phosphorylation.

How does IL22RA1 contribute to IL22 signaling? 03/01/2022

IL22RA1 enhances IL22 signaling by forming a complex with IL-10R2.

What impact do IL22RA1 polymorphisms have on disease susceptibility? 08/13/2021

IL22RA1 polymorphisms affect disease susceptibility in Crohn's disease.

Is IL22RA1 involved in anti-tumor immunity? 07/01/2021

IL22RA1 is involved in anti-tumor immunity by activating STAT3.

How does IL22RA1 expression change in autoimmune diseases? 05/25/2021

IL22RA1 expression is upregulated in autoimmune diseases like psoriasis.

How does IL22RA1 contribute to epithelial barrier function? 04/28/2021

IL22RA1 enhances epithelial barrier function.

Is IL22RA1 expression tissue-specific? 05/21/2020

IL22RA1 expression is tissue-specific, being high in the liver and skin.

Does IL22RA1 interact with other receptors? 01/20/2020

IL22RA1 interacts with IL-10R2 and IL-20RB.

What is the affinity of IL22 for IL22RA1? 02/13/2016

IL22 has high affinity for IL22RA1.

Does IL22RA1 have alternative splicing variants? 01/05/2016

IL22RA1 has multiple alternative splicing variants.

Customer Reviews (3)

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Reviews
12/18/2022

    High stability in serum.

    09/04/2017

      Suitable for receptor binding.

      10/16/2016

        Effective in autoimmune studies.

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