Active Recombinant Human IL23A Protein IL23A-967H

Active Recombinant Human IL23A Protein

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Active Recombinant Human IL23A Protein

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Specification Gene Information Related Products
Cat.No. : IL23A-967H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL-23 consists of two subunits linked via a disulfide bond: P19, the region of Ala21- Pro189) from Accession# NP_057668, and P40, the region of Ile 23-Ser 328) from Accession# NP_002178.2, was expressed in insect cells.
Description : This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Source : Insect cells
Form : 1 x PBS
Bio-activity : The ED50 is 0.2 - 0.8 ng/ml, corresponding to a specific activity of 5 - 1.25 x 10^6 units/mg determined by mouse splenocyte IL-17A secretion, which is induced by hIL-23 in a dose dependent manner.
Molecular Mass : 53.3 kDa
Endotoxin : Less than 0.01 ng per µg protein as determined by the LAL method.
Purity : >95%, as determined by Coomassie stained SDS-PAGE.
Concentration : Protein formulated and vialed at >50 ug/mL in specified buffer
Gene Name : IL23A interleukin 23, alpha subunit p19 [ Homo sapiens ]
Official Symbol : IL23A
Synonyms : IL23A; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; IL 23; IL 23A; IL23P19; interleukin six; G CSF related factor; P19; SGRF; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor; IL-23; IL-23A; MGC79388;
Gene ID : 51561
mRNA Refseq : NM_016584
Protein Refseq : NP_057668
MIM : 605580
UniProt ID : Q9NPF7

Products Types

◆ Recombinant Protein

IL23A-179HRecombinant Active Human IL23A Protein, His-tagged(N-ter)+Inquiry
IL23A-1172HRecombinant Human IL23A Protein, His (Fc)-Avi-tagged+Inquiry
Il23a-2304MRecombinant Mouse Il23a Protein, His-tagged+Inquiry
IL23A-364CRecombinant Cynomolgus Monkey IL23A Protein, His (Fc)-Avi-tagged+Inquiry
Il23a-3516MRecombinant Mouse Il23a Protein, Myc/DDK-tagged+Inquiry

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◆ Lysates

IL23A-5231HCLRecombinant Human IL23A 293 Cell Lysate+Inquiry

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Related Gene

IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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