Active Recombinant Human IL2RA Protein
Cat.No. : | IL2RA-948H |
Product Overview : | Recombinant Human IL2RA was expressed in Hi-5 insect cells. |
- Specification
- Gene Information
- Related Products
Description : | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
Source : | Hi-5 insect cells |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 |
Bio-activity : | Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5 - 1.5 ug/ml. |
Molecular Mass : | 24.8 kDa |
AA Sequence : | ELCDDDPPEIPHATFKAMAYKEGTM LNCECKRGFRRIKSGSLYMLCTGNS SHSSWDNQCQCTSSATRNTTKQVTP QPEEQKERKTTEMQSPMQPVDQASL PGHCREPPPWENEATERIYHFVVGQ MVYYQCVQGYRALHRGPAESVCKMT HGKTRWTQPQLICTGEMETSQFPGE EKPQASPEGRPESETSCLVTTTDFQ IQTEMAATMETSIFTTEYQ |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein in the desired concentration in proper buffer |
Gene Name : | IL2RA interleukin 2 receptor, alpha [ Homo sapiens ] |
Official Symbol : | IL2RA |
Synonyms : | IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10; |
Gene ID : | 3559 |
mRNA Refseq : | NM_000417 |
Protein Refseq : | NP_000408 |
MIM : | 147730 |
UniProt ID : | P01589 |
Products Types
◆ Recombinant Protein | ||
IL2RA-5197H | Recombinant Human IL2RA Protein | +Inquiry |
Il2ra-4513M | Recombinant Mouse Il2ra Protein, His (Fc)-Avi-tagged | +Inquiry |
IL2RA-179I | Active Recombinant Human IL2RA Protein (205 aa), His-tagged | +Inquiry |
IL2RA-5198H | Recombinant Human IL2RA Protein | +Inquiry |
Il2ra-1677M | Recombinant Mouse Il2ra Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL2RA-2907HCL | Recombinant Human IL2RA cell lysate | +Inquiry |
IL2RA-2024MCL | Recombinant Mouse IL2RA cell lysate | +Inquiry |
IL2RA-1015CCL | Recombinant Cynomolgus IL2RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket