Active Recombinant Human Interleukin 16 IL16-534H

Active Recombinant Human Interleukin 16


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Active Recombinant Human Interleukin 16

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Cat.No. : IL16-534H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human IL16 was expressed in E. coli and purified by using conventional chromatography techniques.
Description : IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
Source : Human
Host : E.coli
Form : Supplied as a lyophilized powder.
Purity : >98% pure by SDS PAGE and HPLC
Molecular Mass : 13.5 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity : Determined by its ability ot chemoattract human CD4+ T-lymphoytes using a concentration range of 50.0-100.0 ng/ml.
Storage : Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
PDB rendering basedon 1i16. :

Gene Name : IL16 interleukin 16 [ Homo sapiens ]
Official Symbol : IL16
Synonyms : IL16; FLJ16806; FLJ42735; FLJ44234; LCF; prIL-16; Interleukin-16; Lymphocyte Chemoattractant Factor; prIL-16; IL-16; HsT19289; interleukin-16 precursor; interleukin 16 (lymphocyte chemoattractant factor)
Gene ID : 3603
mRNA Refseq : NM_004513
Protein Refseq : NP_004504
MIM : 603035
UniProt ID : Q14005
Chromosome Location : 15q26.3
Pathway : immune response; induction of positive chemitaxis; leukocyte chemitaxis
Function : cytokine activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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