Active Recombinant Human Interleukin 16
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Cat.No. : | IL16-534H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human IL16 was expressed in E. coli and purified by using conventional chromatography techniques. |
Description : | IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity. |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a lyophilized powder. |
Purity : | >98% pure by SDS PAGE and HPLC |
Sequence : | Region of IL16 protein corresponding to amino acids SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S. |
Molecular Mass : | 13.5 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Bioactivity : | Determined by its ability ot chemoattract human CD4+ T-lymphoytes using a concentration range of 50.0-100.0 ng/ml. |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
PDB rendering basedon 1i16. : |
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Gene Name : | IL16 interleukin 16 [ Homo sapiens ] |
Official Symbol : | IL16 |
Synonyms : | IL16; FLJ16806; FLJ42735; FLJ44234; LCF; prIL-16; Interleukin-16; Lymphocyte Chemoattractant Factor; prIL-16; IL-16; HsT19289; interleukin-16 precursor; interleukin 16 (lymphocyte chemoattractant factor) |
Gene ID : | 3603 |
mRNA Refseq : | NM_004513 |
Protein Refseq : | NP_004504 |
MIM : | 603035 |
UniProt ID : | Q14005 |
Chromosome Location : | 15q26.3 |
Pathway : | immune response; induction of positive chemitaxis; leukocyte chemitaxis |
Function : | cytokine activity; protein binding |
◆ Recombinant Protein
IL16-2055R | Recombinant Rhesus Macaque IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL16-136M | Recombinant Mouse IL16 Protein | +Inquiry |
IL16-3143H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL16-135H | Recombinant Human IL16 Protein | +Inquiry |
IL16-1007C | Recombinant Chicken IL16 Protein, His-tagged | +Inquiry |
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◆ Native Protein
IL16-29736TH | Native Human IL16 | +Inquiry |
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◆ Lysates
IL16-5245HCL | Recombinant Human IL16 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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