Active Recombinant Human NOTCH3 protein, His-tagged
Cat.No. : | NOTCH3-948H |
Product Overview : | Recombinant Human NOTCH3 protein(Q9UM47)(Ala1378-Ser1640) is expressed from Expi293 with His tag at the C-terminal. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human Notch 3, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Notch 3 Antibody, hFc Tag with the EC50 of 8.2ng/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 30.18 kDa. Due to furin-like protease cleavage and glycosylation, the protein migrates to 27-30 kDa and 10-12 kDa based on Tris-Bis PAGE result. |
Protein Length : | Ala1378-Ser1640 |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE > 95% as determined by HPLC |
Storage : | -20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles. |
Reconstitution : | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Publication : |
The Special Role of JAK/STAT, and Notch Signaling Pathways in Cancer Pathogenesis (2023)
|
Gene Name : | NOTCH3 notch 3 [ Homo sapiens ] |
Official Symbol : | NOTCH3 |
Synonyms : | NOTCH3; notch 3; CADASIL, Notch (Drosophila) homolog 3 , Notch homolog 3 (Drosophila); neurogenic locus notch homolog protein 3; CASIL; Notch homolog 3; CADASIL; |
Gene ID : | 4854 |
mRNA Refseq : | NM_000435 |
Protein Refseq : | NP_000426 |
MIM : | 600276 |
UniProt ID : | Q9UM47 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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