Active Recombinant Human OSM, Fc-tagged, Biotinylated
| Cat.No. : | OSM-657H |
| Product Overview : | The recombinant human OSM-Fc is expressed as a 433-amino acid active form consisting of Ala26 - Arg220 region of (UniProt accession #P13725) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
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| Source : | Human cells |
| Species : | Human |
| Tag : | Fc |
| Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
| Bio-activity : | Stimulates TF-1 human erythroleukemic cell proliferation assay with an ED50 typically 0.2 - 0.5 ng/ml. Supports the maintenance of embryonic stem (ES) cell pluripotency and germline competency. |
| Molecular Mass : | Calculated molecular mass (kDa): 48.7; Estimated by SDS-PAGE under reducing condition (kDa): ~55 |
| AA Sequence : | AAIGSCSKEYRVLLGQLQKQTDLMQ DTSRLLDPYIRIQGLDVPKLREHCR ERPGAFPSEETLRGLGRRGFLQTLN ATLGCVLHRLADLEQRLPKAQDLER SGLNIEDLEKLQMARPNILGLRNNI YCMAQLLDNSDTAEPTKAGRGASQ PPTPTPASDAFQRKLEGCRFLHGYH RFMHSVGRVFSKWGESPNRSRSTTE NLYFQGSTGTHTCPPCPAPELLGG PSVFLFPPKPKDTLMISRTPEVTCV VVDVSHEDPEVKFNWYVDGVEVHNA KTKPREEQYNSTYRVVSVLTVLHQ DWLNGKEYKCKVSNKALPAPIEKTI SKAKGQPREPQVYTLPPSREEMTKN QVSLTCLVKGFYPSDIAVEWESNG QPENNYKTTPPVLDSDGSFFLYSKL TVDKSRWQQGNVFSCSVMHEALHNH YTQKSLSLSPGK |
| Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal> |
| Purity : | >95% judged by SDS-PAGE under reducing condition |
| Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
| Gene Name : | OSM oncostatin M [ Homo sapiens ] |
| Official Symbol : | OSM |
| Synonyms : | OSM; oncostatin M; oncostatin-M; MGC20461; |
| Gene ID : | 5008 |
| mRNA Refseq : | NM_020530 |
| Protein Refseq : | NP_065391 |
| MIM : | 165095 |
| UniProt ID : | P13725 |
| Chromosome Location : | 22q12.2 |
| Pathway : | Adipogenesis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
| Function : | cytokine activity; growth factor activity; oncostatin-M receptor binding; |
Products Types
| ◆ Recombinant Protein | ||
| OSM-31H | Recombinant Human OSM Protein | +Inquiry |
| OSM-064O | Recombinant Human OSM Protein (209 aa) | +Inquiry |
| OSM-220H | Recombinant Human OSM Protein | +Inquiry |
| OSM-3870R | Recombinant Rat OSM Protein, His (Fc)-Avi-tagged | +Inquiry |
| Osm-4619M | Recombinant Mouse Osm Protein, Myc/DDK-tagged | +Inquiry |
| ◆ Lysates | ||
| OSM-1766HCL | Recombinant Human OSM cell lysate | +Inquiry |
| OSM-1659MCL | Recombinant Mouse OSM cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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