Active Recombinant Human PDGFA Protein, Animal Free

• Cat.No.: PDGFA-44H
• Product Overview: Recombinant Human PDGFA Protein without tag was expressed in Human cells.
  Animal Free and Xeno Free

Specification

• Description: PDGF is not one molecule but three, each a dimeric combination of two distinct but structurally related peptide chains designated A and B. The dimeric isoforms PDGFaa, ab and bb are differentially expressed in various cell types and their effects are mediated through two distinct receptors, termed α and β. The PDGFs play an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. They are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development.
• Source: Human cells
• Species: Human
• Bio-activity: The activity was measured by its ability to stimulate the proliferation of 3T3 cells.
• Molecular Mass: 35, 40, 45 kDa
• Endotoxin: <0.5 EU/ μg
• Purity: High Purity, >95% by SDS-PAGE
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
• Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Gene Information

• Gene Name: PDGFA platelet derived growth factor subunit A [ Homo sapiens (human) ]
• Official Symbol: PDGFA
• Synonyms: PDGFA; platelet derived growth factor subunit A; PDGF1; PDGF-A; platelet-derived growth factor subunit A; PDGF A-chain; PDGF subunit A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide
• Gene ID: 5154
• mRNA Refseq: NM_033023
• Protein Refseq: NP_148983
• MIM: 173430
• UniProt ID: P04085