Active Recombinant Human PDGFRB protein(Met1-Lys531), His-tagged
Cat.No. : | PDGFRB-2187H |
Product Overview : | Recombinant Human PDGFRβ (NP_002600.1) extracellular domain (Met 1-Lys 531) was expressed in HEK293, with a C-terminal polyhistidine tag. |
Availability | February 09, 2025 |
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Species : | Human |
Source : | HEK293 |
Tag : | His |
ProteinLength : | Met1-Lys531 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized PDGFRβ-His at 10 μg/ml (100 μl/well) can bind Cynomolgus PDGFB, The EC50 of Cynomolgus PDGFB is 3-8 ng/ml. |
Molecular Mass : | The secreted recombinant human PDGFRβ comprises 510 amino acids and predicts a molecular mass of 57.6 kDa. It migrates as an approximately 95-100 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name | PDGFRB platelet-derived growth factor receptor, beta polypeptide [ Homo sapiens ] |
Official Symbol | PDGFRB |
Synonyms | PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1; |
Gene ID | 5159 |
mRNA Refseq | NM_002609 |
Protein Refseq | NP_002600 |
MIM | 173410 |
UniProt ID | P09619 |
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Not For Human Consumption!
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