Active Recombinant Human SIGLEC8 Protein, Fc-tagged

• Cat.No.: SIGLEC8-6584H
• Product Overview: Recombinant Human SIGLEC8 Protein (Met17-Ala363) was expressed in NS0 cells with C-terminal Human IgG1 Fc tag.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: 17-363 a.a.
• Form: Powder
• Bio-activity: Measured by its binding ability in a functional ELISA. When Biotinylated Sialyl Lewis X was immobilized at 0.05 μg/mL (100 μL/well), it binds Recombinant Human Siglec-8 Fc Chimera. The concentration of Human Siglec-8 Fc Chimera that produces 50% of the optimal binding response is approximately 0.2-1.2 μg/mL.
• Molecular Mass: 68-88 kDa (SDS-PAGE under reducing conditions.)
• Storage: Store at -20 to -70 centigrade.
• Storage buffer: PBS solution with Trehalose.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.

Gene Information

• Gene Name: SIGLEC8 sialic acid binding Ig-like lectin 8 [ Homo sapiens ]
• Official Symbol: SIGLEC8
• Synonyms: SIGLEC8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC 8; SIGLEC8L; SAF-2; CDw329; sialoadhesin family member 2; SIGLEC-8
• Gene ID: 27181
• mRNA Refseq: NM_014442
• Protein Refseq: NP_055257
• MIM: 605639
• UniProt ID: Q9NYZ4