Active Recombinant Human VTN Protein, Animal Free

Cat.No. : VTN-54H
Product Overview : Recombinant Human VTN Protein without tag was expressed in Human cells.
Animal Free and Xeno Free
  • Specification
  • Gene Information
  • Related Products
Description : Vitronectin is a secreted glycoprotein detected as a mixture of 75 kilodalton ( kDa) and 65 kDa polypeptides in serum and the extracellular matrix. It primarily in monomeric form, but it can also be found as a dimer after endogenous cleavage. Vitronectin can support cell adhesion and spreading through binding to various integrins and other proteoglycans. The cell-binding site of vitronectin involves a common cell-attachment tripeptide Arg-Gly-Asp Additionally, recombinant vitronectin can function as a chemically-defined matrix component in human embryonic stem cell and induced pluripotent stem cell.
Source : Human cells
Species : Human
Bio-activity : Recombinant Human Vitronectin promotes attachment of adherent cell in serum free, such as hESC and iPSC. Measured by the ability of the immobilized protein to support the adhesion of HUVEC cells, when 5 x 104 cells/well are added to Vitronectin coated plates (5 μg/mL with 100 μL/well), approximately >60% will adhere after 30 minutes at 37 centigrade.
Molecular Mass : ~75 kDa homotrimer
Endotoxin : <0.5 EU/ μg
Purity : High Purity, >95% by SDS-PAGE
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
Reconstitution : Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Gene Name : VTN vitronectin [ Homo sapiens (human) ]
Official Symbol : VTN
Synonyms : VTN; vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S protein); complement S protein; serum spreading factor; somatomedin B; VN; epibolin; S-protein; complement S-protein; serum-spreading factor; V75; VNT;
Gene ID : 7448
mRNA Refseq : NM_000638
Protein Refseq : NP_000629
MIM : 193190
UniProt ID : P04004

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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