| Species : |
Monkey |
| Source : |
Yeast |
| Tag : |
Non |
| Protein Length : |
2-776 aa |
| Description : |
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies. |
| Form : |
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant. |
| Bio-activity : |
Immobilized Cynomolgus Tau Protein, Tag Free at 5 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.1-8 ng/mL. |
| Molecular Mass : |
The protein has a calculated MW of 82.9 kDa. |
| Endotoxin : |
Less than 0.01 EU/μg by the LAL method/rFC method. |
| Purity : |
>85% as determined by SDS-PAGE. |
| Storage : |
This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. |
| Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
