Active Recombinant Mouse Fgf23
Cat.No. : | Fgf23-27M |
Product Overview : | Recombinant murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50 for this effect is 0.3-0.5 μg/ml, in the presence of murine Klotho and heparin. |
Molecular Mass : | 25.5 kDa |
AA Sequence : | MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Gene Name : | Fgf23 fibroblast growth factor 23 [ Mus musculus (house mouse) ] |
Official Symbol : | Fgf23 |
Synonyms : | Fgf23; fibroblast growth factor 23; fibroblast growth factor 23; FGF-23 |
Gene ID : | 64654 |
mRNA Refseq : | NM_022657 |
Protein Refseq : | NP_073148 |
UniProt ID : | Q9EPC2 |
Chromosome Location : | 6 F3; 6 |
Pathway : | Activated point mutants of FGFR2; DAP12 interactions; Downstream signal transduction |
Function : | fibroblast growth factor receptor binding; growth factor activity; protein binding |
Products Types
◆ Recombinant Protein | ||
FGF23-036H | Active Recombinant Human FGF23 Protein | +Inquiry |
FGF23-1990R | Recombinant Rat FGF23 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGF23-118F | Active Recombinant Human FGF23 Protein (228 aa) | +Inquiry |
FGF23-298H | Active Recombinant Human FGF23 Protein (Tyr25-Ile251), C-His tagged, Animal-free, Carrier-free | +Inquiry |
FGF23-684H | Recombinant Human FGF23 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FGF23-6241HCL | Recombinant Human FGF23 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionFGF23 levels are elevated in chronic kidney disease, contributing to mineral imbalance.
High FGF23 levels are associated with increased cardiovascular risk.
It decreases renal phosphate reabsorption and 1,25-dihydroxyvitamin D production.
Mutations in FGF23 or related proteins can lead to dysregulated phosphate metabolism.
Strategies include phosphate binders and FGF23 antibodies to manage elevated FGF23 levels.
FGF23 is primarily produced in bone.
FGF23 regulates phosphate and vitamin D metabolism.
Customer Reviews (3)
Write a reviewExcellent results, high purity.
Reliable and effective product.
Quick delivery, product works.
Ask a Question for All Fgf23 Products
Required fields are marked with *
My Review for All Fgf23 Products
Required fields are marked with *
Inquiry Basket