FGF23
-
Official Full Name
fibroblast growth factor 23 -
Overview
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] -
Synonyms
FGF23;fibroblast growth factor 23;ADHR;FGFN;HYPF;HPDR2;PHPTC;phosphatonin;tumor-derived hypophosphatemia inducing factor
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- Insect Cells
- E.coli
- HEK293
- Mammalian Cells
- Human Cells
- Human
- Yeast
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Fc
- T7
- Flag
- GST
- Avi
- DDK
- Myc
Involved Pathway
FGF23 involved in several pathways and played different roles in them. We selected most pathways FGF23 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FGF23 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGF23 itself. We selected most functions FGF23 had, and list some proteins which have the same functions with FGF23. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
FGF23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF23 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF23.
FGF23 Related Signal Pathway
Resources
Related Services
Related Products
References
- Lindberg, I; Pang, HW; et al. FGF23 is Endogenously Phosphorylated in Bone Cells. JOURNAL OF BONE AND MINERAL RESEARCH 30:431-436(2015).
- Moe, SM; Chen, NX; et al. Anti-Sclerostin Antibody Treatment in a Rat Model of Progressive Renal Osteodystrophy. JOURNAL OF BONE AND MINERAL RESEARCH 30:539-549(2015).
