Active Recombinant Mouse Il13
Cat.No. : | Il13-16M |
Product Overview : | A DNA sequence encoding the mouse IL13 (Pro22-Phe131) was expressed and purified. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types. |
Source : | Human Cells |
Species : | Mouse |
Predicted N Terminal : | Pro 22 |
Form : | Lyophilized from sterile PBS, pH 7.5 |
Bio-activity : | Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is typically 2-10 ng/mL. |
Molecular Mass : | The recombinant mouse IL13 consists of 110 amino acids and predicts a molecular mass of 12.1 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C |
Storage : | Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Publication : |
IFN-γ Limits Immunopathogenesis but Delays Fungal Clearance during Pneumocystis Pneumonia (2023)
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Gene Name : | Il13 interleukin 13 [ Mus musculus (house mouse) ] |
Official Symbol : | Il13 |
Synonyms : | Il13; interleukin13; Il-13;interleukin-13;OTTMUSP00000005816; T-cell activation protein P600; IL-13 |
Gene ID : | 16163 |
mRNA Refseq : | NM_008355 |
Protein Refseq : | NP_032381 |
UniProt ID : | P20109 |
Chromosome Location : | 11 B1.3; 11 31.98 cM |
Pathway : | Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Glucocorticoid receptor regulatory network |
Function : | cytokine activity; interleukin-13 receptor binding; cytokine receptor binding |
Products Types
◆ Recombinant Protein | ||
Il13-256I | Active Recombinant Mouse Il13 Protein, His-tagged | +Inquiry |
Il13-087M | Active Recombinant Mouse Il13 Protein | +Inquiry |
IL13-4350R | Recombinant Rabbit IL13 Protein | +Inquiry |
Il13-144M | Recombinant Active Mouse IL13 Protein, His-tagged(C-ter) | +Inquiry |
Il13-088M | Recombinant Mouse Il13 Protein | +Inquiry |
◆ Lysates | ||
IL13-2922HCL | Recombinant Human IL13 cell lysate | +Inquiry |
IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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