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Active Recombinant Mouse IL18, MIgG2a Fc-tagged

Cat.No. : IL18-639M
Product Overview : The extracellular domain of mouse IL-18 (NP_032386.1)(Asn36-Ser192) is fused to the N-terminus of the Fc region of a mouse IgG2a was expressed in CHO cell.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity inspleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively splicedtranscript variants encoding different isoforms have been found for this gene
Source : CHO cells
Species : Mouse
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Induction of IFN-γ in response to the recombinant mouse IL-18 was measured.
Molecular Mass : 45KDa (monomer)
AA Sequence : Asn36-Ser192
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Il18 interleukin 18 [ Mus musculus ]
Official Symbol : IL18
Synonyms : IL18; interleukin 18; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Igif; Il-18;
Gene ID : 16173
mRNA Refseq : NM_008360
Protein Refseq : NP_032386
Pathway : African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Hypertrophy Model, organism-specific biosystem;
Function : cytokine activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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