Active Recombinant Mouse Il3 Protein, His-Tagged
Cat.No. : | Il3-01M |
Product Overview : | Recombinant mouse Il3 Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. Interleukin 3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells or, with the addition of IL-7, into lymphoid progenitor cells. In addition, IL-3 stimulates proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells), in conjunction with other cytokines, e.g., Erythropoietin (EPO), Granulocyte macrophage colony-stimulating factor (GM-CSF), and IL-6. It is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MDTHRLTRTLNCSSIVKEIIGKLPE PELKTDDEGPSLRNKSFRRVNLSKF VESQGEVDPEDRYVIKSNLQKLNCC LPTSANDSALPGVFIRDLDD FRKKLRFYMVHLNDLETVLTSRPPQ PASGSVSPNRGTVEC with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measure by its ability to induce NFS-60 cells proliferation. The ED50 for this effect is <85 pg/mL. The specific activity of recombinant mouse IL-3 is approximately >1x 10^7 IU/mg. |
Purity : | ≥95% as determined by SDS-PAGE and HPLC. Purified by Ni-NTA chromatography. |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Il3 interleukin 3 [ Mus musculus (house mouse) ] |
Official Symbol : | Il3 |
Synonyms : | BPA; PSF; HCGF; Il-3; MCGF; Csfmu |
Gene ID : | 16187 |
mRNA Refseq : | NM_010556.4 |
Protein Refseq : | NP_034686.2 |
UniProt ID : | P01586 |
Products Types
◆ Lysates | ||
IL3-607HCL | Recombinant Human IL3 cell lysate | +Inquiry |
IL3-445RCL | Recombinant Rat IL3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket