Active Recombinant Mouse Il33 Protein, His-Tagged
Cat.No. : | Il33-01M |
Product Overview : | Recombinant mouse Il33 Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 33 (IL-33) is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for ST2 (IL1RL1), an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and group 2 innate lymphocytes. It is expressed by a wide variety of cell types, including fibroblasts, mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MSIQGTSLLTQSPASLSTYNDQSVS FVLENGCYVINVDDSGKDQEQDQVL LRYYESPCPASQSGDGVDGKKLMVN MSPIKDTDIWLHAND KDYSVELQRGDVSPPEQAFFVLHKK SSDFVSFECKNLPGTYIGVKDNQLA LVEEKDESCNNIMFKLSKI with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measure by its ability to induce proliferation in D10.G4.1 cells. The ED50 for this effect is <40 pg/mL. The specific activity of recombinant mouse IL-33 is > 2 x 10^7 IU/mg. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Il33 interleukin 33 [ Mus musculus (house mouse) ] |
Official Symbol : | Il33 |
Synonyms : | Il-33; Il1f11; NF-HEV; 9230117N10Rik |
Gene ID : | 77125 |
mRNA Refseq : | NM_001164724.2 |
Protein Refseq : | NP_001158196.1 |
UniProt ID : | Q8BVZ5 |
Products Types
◆ Recombinant Protein | ||
Il33-192M | Recombinant Active Mouse IL33 Protein, His-tagged(C-ter) | +Inquiry |
Il33-157M | Recombinant Mouse Il33 Protein | +Inquiry |
IL33-45H | Recombinant Human IL33 Protein, N-Avi tagged, Biotinylated | +Inquiry |
IL33-2313H | Recombinant Human IL33 Protein, His-tagged | +Inquiry |
IL33-191H | Recombinant Active Human IL33 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL33-5226HCL | Recombinant Human IL33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (6)
Ask a questionIt can be used to detect immune cells such as macrophages and dendritic cells.
This protein applied in immunology, drug research, life science and other fields.
Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.
IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.
The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.
Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.
Customer Reviews (3)
Write a reviewGood solubility and is easy to operate and purify.
Effectively mimics the function of the target protein in vitro.
IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.
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