Recombinant Mouse Il36g Protein

• Cat.No.: Il36g-176M
• Product Overview: Recombinant Mouse Il36g Protein without tag was expressed in E. coli.

Specification

• Description: Interleukin 36 gamma (IL-36 £) is a member of the interleukin 1 (IL-1) cytokine family and protects against pathogens in the skin, lung, and stomach epithelial barriers. IL-36 £ binds the interleukin-1 receptor accessory protein (IL-1RAcP) and the orphan IL-1R-related protein 2 (IL-1Rrp2) receptors to activate NF-kB and MAP kinase signaling pathways, resulting in the induced production of inflammatory cytokines and chemokines.
• Source: E. coli
• Species: Mouse
• Bio-activity: No biological activity data is available at this time.
• Molecular Mass: Monomer, 17.5 kDa (153 aa)
• AA Sequence: MGRETPDFGEVFDLDQQVWIFRNQA LVTVPRSHRVTPVSVTILPCKYPES LEQDKGIAIYLGIQNPDKCLFCKEV NGHPTLLLKEEKILDLYHHPEPMKP FLFYHTRTGGTSTFESVAFPGHYIA SSKTGNPIFLTSKKGEYYNINFNLD IKS
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
• Reconstitution: Sterile 10 mM sterile HCl at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: Il36g interleukin 36G [ Mus musculus (house mouse) ]
• Official Symbol: Il36g
• Synonyms: Il36g; interleukin 36G; If36g; Il1f9; IL-36gamma; interleukin-36 gamma; IL-1F9; interleukin 1 family, member 9
• Gene ID: 215257
• mRNA Refseq: NM_153511
• Protein Refseq: NP_705731
• UniProt ID: Q8R460

Reviews

05/29/2022

When experimenting with IL36G, the results are very reproducible.

04/14/2022

Production process of IL36G products is environmentally friendly and sustainable, in line with the concept of green production.

01/06/2022

IL36G has good solubility and ion exchange ability, which is convenient for subsequent experimental treatment and purification.

Q&As

Can IL36G treat other inflammatory diseases?

It is currently mainly used in the treatment of skin inflammatory diseases, and the therapeutic potential of other inflammatory diseases needs further study.

What are the main application areas of IL36G in scientific research?

It is mainly used in the research of the mechanism of skin inflammation and the development of new drugs.

What is the production process of IL36G?

The production of IL36G usually adopts genetic engineering technology, its genes are introduced into the expression host, and pure is obtained through fermentation, purification and other steps.

What are the advantages of IL36G in the treatment of skin inflammation compared with other drugs?

IL36G can be targeted to inhibit inflammation by directly acting on inflammation-related signaling pathways, which may be more effective than other drugs.

What is the mechanism of action of IL36G?

IL36G activates inflammation-related signaling pathways by binding to its receptors, promoting the activation of immune cells and the release of inflammatory factors.

What are the side effects of IL36G?

The side effects of IL36G may include skin irritation, allergic reactions, etc. The specific side effects can vary from individual to individual.